BDBM50232158 CHEMBL4062685

SMILES COc1c(Cl)cc(cc1CN1CCN(CC1)C(C)=O)-c1ccc(s1)C(=O)c1c(F)ccc(O)c1F

InChI Key InChIKey=BVOMLTQEDYNOMJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50232158   

Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50232158(CHEMBL4062685)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 assessed as reduction in activation of [2,4,6,7-3H]-E1 substrate to E2 after 10 mins in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50232158(CHEMBL4062685)
Affinity DataIC50:  21nMAssay Description:Inhibition of human placental microsomal 17beta-HSD2 using [2,4,6,7-3H]-E2 as substrate after 20 mins in presence of NAD+ by RP-HPLC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed