BDBM50233774 CHEMBL401405::tert-butyl (R)-1-oxo-1-((3-((R)-1-phenylethyl)-3H-imidazo[4,5-b]pyridin-2-yl)methylamino)-3-(2-(trifluoromethyl)phenyl)propan-2-ylcarbamate

SMILES C[C@H](c1ccccc1)n1c(CNC(=O)[C@@H](Cc2ccccc2C(F)(F)F)NC(=O)OC(C)(C)C)nc2cccnc12

InChI Key InChIKey=GCVRLFSAZVKLNE-NTKDMRAZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50233774   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50233774(CHEMBL401405 | tert-butyl (R)-1-oxo-1-((3-((R)-1-p...)
Affinity DataIC50:  191nMAssay Description:Blockade of human Nav1.7 channel expressed in HEK293 cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed