BDBM50234059 CHEMBL4087821::US9765018, Example 63

SMILES COc1ccc(cc1C(O)=O)-c1ccc(Oc2ccccc2C(C)C)c(NC(=O)Nc2ccc(C)cc2)c1

InChI Key InChIKey=PGRVQMQFSUHFPQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234059   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50234059(CHEMBL4087821 | US9765018, Example 63)
Affinity DataIC50:  1.60E+3nMAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50234059(CHEMBL4087821 | US9765018, Example 63)
Affinity DataIC50:  340nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as inhibition of kynurenine production preincubated with cells followed by IFN-g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed