BDBM50235313 CHEMBL4074825

SMILES Cc1c(O)c2cc(Cl)ccc2nc1C(=O)N1CCN(CC1)c1ccccc1

InChI Key InChIKey=LHULJLLNFWPBMG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50235313   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50235313(CHEMBL4074825)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50235313(CHEMBL4074825)
Affinity DataIC50:  1.13E+3nMAssay Description:Inhibition of recombinant human COX2 using arachidonic acid as substrate assessed as decrease in PGF2 production preincubated for 15 mins followed by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed