BDBM50235345 CHEMBL4105278

SMILES NS(=O)(=O)c1ccc(Nc2nc(-c3ccccc3)c3nc[nH]c3n2)cc1

InChI Key InChIKey=GETVVUWUPLHXBE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50235345   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235345(CHEMBL4105278)
Affinity DataIC50:  730nMAssay Description:Inhibition of recombinant human CDK1/Cyclin B expressed in baculovirus infected Sf9 cells using PKTPKKAKKL-NH2 as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235345(CHEMBL4105278)
Affinity DataIC50:  570nMAssay Description:Inhibition of recombinant human full-length C-terminal His6-tagged Cdk9/human full-length Cyclin T expressed in baculovirus infected Sf21 insect cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235345(CHEMBL4105278)
Affinity DataIC50:  6.80E+3nMAssay Description:In vitro inhibitory concentration against angiotensin-converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2(Bos taurus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235345(CHEMBL4105278)
Affinity DataIC50:  24nMAssay Description:In vitro inhibitory concentration against angiotensin-converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed