BDBM50235361 CHEMBL4074015

SMILES NS(=O)(=O)c1ccc(Nc2nc(C#C)c3nc[nH]c3n2)cc1

InChI Key InChIKey=IOGIUPJAOMXLRJ-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50235361   

TargetCyclin-A2(Bos taurus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235361(CHEMBL4074015)
Affinity DataIC50:  830nMAssay Description:Inhibition of human GST-tagged CDK2/bovine His-tagged Cyclin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235361(CHEMBL4074015)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of human CDK1 by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235361(CHEMBL4074015)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235361(CHEMBL4074015)
Affinity DataIC50:  140nMAssay Description:Inhibition of human NEK2 by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235361(CHEMBL4074015)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human ChK2 by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235361(CHEMBL4074015)
Affinity DataIC50:  3.61E+4nMAssay Description:Inhibition of human CDK7 by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235361(CHEMBL4074015)
Affinity DataIC50:  4.13E+4nMAssay Description:Inhibition of human CDK9 by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235361(CHEMBL4074015)
Affinity DataIC50:  3.37E+4nMAssay Description:Inhibition of human Plk1 by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235361(CHEMBL4074015)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human P70S6K by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235361(CHEMBL4074015)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of human ChK1 by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed