BDBM50235595 CHEMBL4081077

SMILES Oc1nsnc1C(=O)Nc1c(F)c(F)c(-c2cccc(OC(F)(F)F)c2)c(F)c1F

InChI Key InChIKey=QGYWCAYZXMXQQT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235595   

TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Torino

Curated by ChEMBL
LigandPNGBDBM50235595(CHEMBL4081077)
Affinity DataIC50:  44nMAssay Description:Inhibition of recombinant human N-terminal truncated GST-tagged DHFR (31 to 395 residues) expressed in Escherichia coli BL21(DE3) pyrD using DHO as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed