BDBM50236255 19-methyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one::CHEMBL258437

SMILES Cn1cc-2c(CCc3c-2c2C(=O)NCc2c2c4ccccc4[nH]c32)n1

InChI Key InChIKey=GOPWMXCRSJOJRB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50236255   

TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50236255(19-methyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human recombinant TIE2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50236255(19-methyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2...)
Affinity DataIC50:  16nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50236255(19-methyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2...)
Affinity DataIC50:  1.36E+3nMAssay Description:Inhibition of TIE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed