BDBM50236264 19-methyl-7-[(1E)-1-[(propan-2-yloxy)imino]ethyl]-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one::CHEMBL258000

SMILES CC(C)O\N=C(/C)c1ccc2[nH]c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1

InChI Key InChIKey=ZZOUIAPNOGIDSZ-VFLNYLIXSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50236264   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50236264(19-methyl-7-[(1E)-1-[(propan-2-yloxy)imino]ethyl]-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50236264(19-methyl-7-[(1E)-1-[(propan-2-yloxy)imino]ethyl]-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC cells at 50 nM relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50236264(19-methyl-7-[(1E)-1-[(propan-2-yloxy)imino]ethyl]-...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human recombinant TIE2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed