BDBM50236282 CHEMBL4104895
SMILES Cl.CC1(C)N=C(N)N=C(N)N1OCCOc1cccc(c1)C(=O)\C=C\c1ccccc1
InChI Key InChIKey=AYAVEBPLSLPUBI-VAWYXSNFSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50236282
TargetDihydrofolate reductase(Homo sapiens (Human))
National University Of Singapore
Curated by ChEMBL
National University Of Singapore
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human DHFR assessed as reduction in conversion of DHF to THF measured every 30 secs for 6 mins by UV-Vis spectrophotometric...More data for this Ligand-Target Pair
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National University Of Singapore
Curated by ChEMBL
National University Of Singapore
Curated by ChEMBL
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National University Of Singapore
Curated by ChEMBL
National University Of Singapore
Curated by ChEMBL
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of recombinant rat liver thioredoxin reductase after 60 mins by DTNB reduction assayMore data for this Ligand-Target Pair