BDBM50236622 CHEMBL4093788
SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)N[C@H]2CCCC[C@@H]2C(=O)NO)c2ccccc2n1
InChI Key InChIKey=PRUBEBCKVHQBST-GMAHTHKFSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50236622
TargetDisintegrin and metalloproteinase domain-containing protein 17(Mus musculus (Mouse))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of TACE in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated TNFalpha production pretreated for 1 hr followed by LPS stimulati...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Mus musculus (Mouse))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Compound was tested for agonistic activity at Glutamate receptor 6 using HEK293 cellsMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair