BDBM50236943 CHEMBL4093676

SMILES COc1cc(OC)cc(c1)C(=O)\C=C\c1cccnc1

InChI Key InChIKey=ISNNUNAKEIZADX-AATRIKPKSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50236943   

TargetCytochrome P450 1B1(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50236943(CHEMBL4093676)
Affinity DataIC50:  106nMAssay Description:Inhibition of human liver CYP1B1 expressed in Saccharomyces cerevisiae YY7 microsomal membranes using 7-ethoxyresorufin as substrate after 10 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50236943(CHEMBL4093676)
Affinity DataIC50:  306nMAssay Description:Inhibition of human liver CYP1A2 expressed in Saccharomyces cerevisiae YY7 microsomal membranes using CEC as substrate after 10 mins by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A1(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50236943(CHEMBL4093676)
Affinity DataIC50:  879nMAssay Description:Inhibition of human liver CYP1A1 expressed in Saccharomyces cerevisiae YY7 microsomal membranes using 7-ethoxyresorufin as substrate after 10 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed