BDBM50237166 CHEMBL4097330

SMILES CCCN(CCCCOc1ccc2ccnn2c1)[C@H]1CCc2c(O)cccc2C1

InChI Key InChIKey=JQXMVFBXXAKVDC-NRFANRHFSA-N

Data  6 KI  13 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50237166   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237166(CHEMBL4097330)
Affinity DataKi:  0.630nMAssay Description:In vitro binding affinity against Tachykinin receptor 1 in guinea pig ileum using organ bath assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237166(CHEMBL4097330)
Affinity DataKi:  0.710nMAssay Description:Agonist activity at human Dopamine D3 receptor expressed in HEK293T cell membranes coexpressing GalphaoA incubated for 30 mins measured after 75 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237166(CHEMBL4097330)
Affinity DataKi:  0.75nMAssay Description:Displacement of [3H]spiperone from human Dopamine D2S receptor expressed in CHO cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237166(CHEMBL4097330)
Affinity DataKi:  1.5nMAssay Description:In vitro inhibition of human thrombin catalytic activity after 3 min pre incubation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237166(CHEMBL4097330)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]ketanserin from human 5-HT2A receptor expressed in HEK293T cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237166(CHEMBL4097330)
Affinity DataKi:  2.10E+3nMAssay Description:Displacement of [3H]SCH23390 from human Dopamine D1 receptor expressed in HEK293T cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237166(CHEMBL4097330)
Affinity DataEC50:  0.810nMAssay Description:Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells coexpressing renilla luciferase 2-tagged Galphai3 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237166(CHEMBL4097330)
Affinity DataEC50:  14nMAssay Description:Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells assessed as induction of renilla luciferase 2-tagg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237166(CHEMBL4097330)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells coexpressing renilla luciferase 2-tagged Galphai1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237166(CHEMBL4097330)
Affinity DataEC50:  26nMAssay Description:Agonist activity at human Dopamine D2S receptor expressed in HEK293T cell membranes coexpressing Galphai2 incubated for 30 mins measured after 75 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237166(CHEMBL4097330)
Affinity DataEC50:  0.480nMAssay Description:Agonist activity at human Dopamine D3 receptor expressed in HEK293T cell membranes coexpressing GalphaoA incubated for 30 mins measured after 75 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237166(CHEMBL4097330)
Affinity DataEC50:  0.479nMAssay Description:Agonist activity at human Dopamine D3 receptor expressed in HEK293T cell membranes coexpressing GalphaoA incubated for 30 mins measured after 75 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237166(CHEMBL4097330)
Affinity DataEC50:  0.110nMAssay Description:Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells coexpressing renilla luciferase 2-tagged GalphaoB ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237166(CHEMBL4097330)
Affinity DataEC50:  0.130nMAssay Description:Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells coexpressing renilla luciferase 2-tagged GalphaoA ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237166(CHEMBL4097330)
Affinity DataEC50:  3nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237166(CHEMBL4097330)
Affinity DataEC50:  0.610nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237166(CHEMBL4097330)
Affinity DataEC50:  2nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237166(CHEMBL4097330)
Affinity DataEC50:  15.9nMAssay Description:Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells assessed as induction of renilla luciferase 2-tagg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237166(CHEMBL4097330)
Affinity DataEC50:  16nMAssay Description:Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells assessed as induction of renilla luciferase 2-tagg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed