BDBM50237957 4-(2-((2,5-dioxoimidazolidin-4-ylidene)methyl)-1H-pyrrol-1-yl)benzoic acid::CHEMBL399586

SMILES OC(=O)c1ccc(cc1)-n1cccc1\C=C1\NC(=O)NC1=O

InChI Key InChIKey=WMOKBKUDIRNAKD-XYOKQWHBSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50237957   

TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50237957(4-(2-((2,5-dioxoimidazolidin-4-ylidene)methyl)-1H-...)
Affinity DataIC50:  2.81E+4nMAssay Description:Inhibition of human PRL3 expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 1(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50237957(4-(2-((2,5-dioxoimidazolidin-4-ylidene)methyl)-1H-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PRL1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 4(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50237957(4-(2-((2,5-dioxoimidazolidin-4-ylidene)methyl)-1H-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MKP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50237957(4-(2-((2,5-dioxoimidazolidin-4-ylidene)methyl)-1H-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PRL3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine-phosphatase(Homo sapiens (Human))
Sejong University

Curated by ChEMBL
LigandPNGBDBM50237957(4-(2-((2,5-dioxoimidazolidin-4-ylidene)methyl)-1H-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of His-tagged PTPsigma catalytic domain amino acid 1369 to 1948 using DiFMUP as substrate after 20 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed