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BDBM50238208 2,4-dimethoxy-N-(5-methylpyridin-2-yl)benzamide::CHEMBL405914::cid_649849

SMILES: COc1ccc(C(=O)Nc2ccc(C)cn2)c(OC)c1

InChI Key: InChIKey=DXZWNXBIUIRQRE-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50238208   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-alpha


(Homo sapiens)
BDBM50238208
PNG
(2,4-dimethoxy-N-(5-methylpyridin-2-yl)benzamide | ...)
Show SMILES COc1ccc(C(=O)Nc2ccc(C)cn2)c(OC)c1
Show InChI InChI=1S/C15H16N2O3/c1-10-4-7-14(16-9-10)17-15(18)12-6-5-11(19-2)8-13(12)20-3/h4-9H,1-3H3,(H,16,17,18)
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Similars

n/an/a 2.57E+3n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2TH8K3N
More data for this
Ligand-Target Pair
Steroidogenic Factor 1


(Homo sapiens (human))
BDBM50238208
PNG
(2,4-dimethoxy-N-(5-methylpyridin-2-yl)benzamide | ...)
Show SMILES COc1ccc(C(=O)Nc2ccc(C)cn2)c(OC)c1
Show InChI InChI=1S/C15H16N2O3/c1-10-4-7-14(16-9-10)17-15(18)12-6-5-11(19-2)8-13(12)20-3/h4-9H,1-3H3,(H,16,17,18)
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n/an/a>1.22E+3n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2PR7TCX
More data for this
Ligand-Target Pair
Luciferase


(Luciola lateralis)
BDBM50238208
PNG
(2,4-dimethoxy-N-(5-methylpyridin-2-yl)benzamide | ...)
Show SMILES COc1ccc(C(=O)Nc2ccc(C)cn2)c(OC)c1
Show InChI InChI=1S/C15H16N2O3/c1-10-4-7-14(16-9-10)17-15(18)12-6-5-11(19-2)8-13(12)20-3/h4-9H,1-3H3,(H,16,17,18)
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Article
PubMed
n/an/a 610n/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Inhibition of firefly luciferase activity


J Med Chem 51: 4724-9 (2008)


Article DOI: 10.1021/jm8004509
BindingDB Entry DOI: 10.7270/Q2BP02MH
More data for this
Ligand-Target Pair
Steroidogenic Factor 1


(Homo sapiens (human))
BDBM50238208
PNG
(2,4-dimethoxy-N-(5-methylpyridin-2-yl)benzamide | ...)
Show SMILES COc1ccc(C(=O)Nc2ccc(C)cn2)c(OC)c1
Show InChI InChI=1S/C15H16N2O3/c1-10-4-7-14(16-9-10)17-15(18)12-6-5-11(19-2)8-13(12)20-3/h4-9H,1-3H3,(H,16,17,18)
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n/an/a 3.40E+3n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2319T8T
More data for this
Ligand-Target Pair
Nuclear receptor ROR-alpha


(Homo sapiens)
BDBM50238208
PNG
(2,4-dimethoxy-N-(5-methylpyridin-2-yl)benzamide | ...)
Show SMILES COc1ccc(C(=O)Nc2ccc(C)cn2)c(OC)c1
Show InChI InChI=1S/C15H16N2O3/c1-10-4-7-14(16-9-10)17-15(18)12-6-5-11(19-2)8-13(12)20-3/h4-9H,1-3H3,(H,16,17,18)
PDB
MMDB

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CHEMBL
PC cid
PC sid
UniChem

Similars

n/an/a 3.60E+3n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q26Q1VNZ
More data for this
Ligand-Target Pair