BDBM50239286 CHEMBL4084601
SMILES C(CN1CCC(COc2ccc3c(NCCc4ccccc4)ncnc3c2)CC1)Nc1ccnc2ccccc12
InChI Key InChIKey=NPTVLSFKUZXFAO-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50239286
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Cnrs-Pierre Fabre Usr3388
Curated by ChEMBL
Cnrs-Pierre Fabre Usr3388
Curated by ChEMBL
Affinity DataEC50: 3.20E+4nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 3A(Homo sapiens (Human))
Cnrs-Pierre Fabre Usr3388
Curated by ChEMBL
Cnrs-Pierre Fabre Usr3388
Curated by ChEMBL
Affinity DataEC50: 4.90E+3nMAssay Description:Inhibition of human DNMT3A catalytic domain using AdoMet assessed as reduction of methylation in 5'-biotin/3' 6-carboxyfluorescein labeled DNA duplex...More data for this Ligand-Target Pair