BDBM50239289 CHEMBL4096752
SMILES COc1ccc(CCNc2ncnc3cc(OCC4CCN(CCNc5ccnc6ccccc56)CC4)ccc23)cc1
InChI Key InChIKey=ZNPPSNWPCNBCFU-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50239289
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Cnrs-Pierre Fabre Usr3388
Curated by ChEMBL
Cnrs-Pierre Fabre Usr3388
Curated by ChEMBL
Affinity DataEC50: 2.70E+4nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 3A(Homo sapiens (Human))
Cnrs-Pierre Fabre Usr3388
Curated by ChEMBL
Cnrs-Pierre Fabre Usr3388
Curated by ChEMBL
Affinity DataEC50: 3.40E+3nMAssay Description:Inhibition of human DNMT3A catalytic domain using AdoMet assessed as reduction of methylation in 5'-biotin/3' 6-carboxyfluorescein labeled DNA duplex...More data for this Ligand-Target Pair