BDBM50239790 CHEMBL4079276

SMILES Cc1cncc(Cc2cc(no2)-c2ccccc2)c1

InChI Key InChIKey=VFHIZDXRXFCKHF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50239790   

TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50239790(CHEMBL4079276)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of rat CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]-11-deoxycorticosterone as substrate after 6 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50239790(CHEMBL4079276)
Affinity DataIC50:  82nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [1,2-3H]-11-deoxycorticosterone as substrate after 6 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50239790(CHEMBL4079276)
Affinity DataIC50:  5nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]-11-deoxycorticosterone as substrate after 6 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed