BDBM50240679 2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-1-(3-hydroxymethyl-3,4-dihydro-1H-isoquinolin-2-yl)-propan-1-one::2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-(3-hydroxymethyl-1,2,3,4-tetrahydro-2-isoquinolinyl)-(2S)-propan-1-one::CHEMBL328135

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1CO

InChI Key InChIKey=HICLVBHTXPRGHR-OZBJMMHXSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50240679   

TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Cagliary

Curated by ChEMBL
LigandPNGBDBM50240679(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-1-(3-hyd...)
Affinity DataKi:  0.440nMAssay Description:Binding affinity at Opioid receptor delta 1 using rat brain receptor (P2 synaptosome) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Naples

Curated by ChEMBL
LigandPNGBDBM50240679(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-1-(3-hyd...)
Affinity DataKi:  0.440nMAssay Description:Inhibitory concentration against Opioid receptor delta 1 in mouse vas deferens using competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Naples

Curated by ChEMBL
LigandPNGBDBM50240679(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-1-(3-hyd...)
Affinity DataKi:  151nMAssay Description:Inhibition of guinea pig ileum Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Cagliary

Curated by ChEMBL
LigandPNGBDBM50240679(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-1-(3-hyd...)
Affinity DataKi:  151nMAssay Description:Binding affinity for rat brain P2 synaptosome Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Naples

Curated by ChEMBL
LigandPNGBDBM50240679(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-1-(3-hyd...)
Affinity DataEC50: <1.00E+4nMAssay Description:Negative logarithm of the molar concentration for agonist activity at Opioid receptor mu 1 was determined in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed