BDBM50240962 Benzo[b]thiophene-2-carboxylic acid ((S)-1-{(R)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-3-methyl-butyl)-amide::CHEMBL190533::N-((S)-1-((S)-1-(4-(3-(dimethylamino)propoxy)benzyl)pyrrolidin-3-ylamino)-4-methyl-1-oxopentan-2-yl)benzo[b]thiophene-2-carboxamide::SB-328872

SMILES CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)N[C@H]1CCN(Cc2ccc(OCCCN(C)C)cc2)C1

InChI Key InChIKey=HLMWNBIZKQIDFC-BDYUSTAISA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240962   

TargetUrotensin-2 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50240962(Benzo[b]thiophene-2-carboxylic acid ((S)-1-{(R)-1-...)
Affinity DataKi:  110nMAssay Description:Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrotensin-2 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50240962(Benzo[b]thiophene-2-carboxylic acid ((S)-1-{(R)-1-...)
Affinity DataIC50:  631nMAssay Description:Inhibition of hU-II-mediated [Ca2+]i mobilization in HEK293 cells expressing human recombinant Urotensin 2 receptor in FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed