BDBM50241010 CHEMBL4074237

SMILES Cc1cc(F)c(NC(=O)c2ccccc2)cc1Nc1ccc2c(CCc3ccc(cc3C2=O)C(=O)NC[C@@H](O)CO)c1

InChI Key InChIKey=AHUUXOYBZUAGAN-RUZDIDTESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241010   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-Universitaet Tuebingen

Curated by ChEMBL
LigandPNGBDBM50241010(CHEMBL4074237)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of P38 alpha MAPK in human whole blood assessed as reduction in TNF-alpha release after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-Universitaet Tuebingen

Curated by ChEMBL
LigandPNGBDBM50241010(CHEMBL4074237)
Affinity DataIC50:  1nMAssay Description:Inhibition of P38 alpha MAPK (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed