BDBM50241201 CHEMBL4074975

SMILES Nc1nc(Cl)c(cc1F)C#N

InChI Key InChIKey=AIJNOCYLVBYQPU-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241201   

TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241201(CHEMBL4074975)
Affinity DataKd:  1.03E+5nMAssay Description:Binding affinity to full length recombinant human biotin-labeled KHK by SPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKetohexokinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241201(CHEMBL4074975)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed