BDBM50241484 CHEMBL4095861

SMILES CC1CCN(CC1)c1nc(ccc1CNC(=O)Nc1cccc2NC(=O)COc12)C(F)(F)F

InChI Key InChIKey=RTNGFMPUJGMFIJ-UHFFFAOYSA-N

Data  2 KI  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50241484   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50241484(CHEMBL4095861)
Affinity DataKi:  0.630nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cell membranes after 45 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50241484(CHEMBL4095861)
Affinity DataKi:  6.5nMAssay Description:Displacement of [3H]RTX from rat TRPV1 after 45 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50241484(CHEMBL4095861)
Affinity DataKd:  0.589nMAssay Description:Binding affinity to human TRPV1 expressed in CHO cells after 45 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50241484(CHEMBL4095861)
Affinity DataKd:  0.590nMAssay Description:Binding affinity to human TRPV1 expressed in CHO cells after 45 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed