BDBM50241504 3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxylic acid (biphenyl-4-ylmethyl)-amide::AM-2::CHEMBL255374::N-(biphenyl-4-ylmethyl)-3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxamide

SMILES Cc1cc(=O)c(O)c(o1)C(=O)NCc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=ZSZOBVLJWIXXND-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50241504   

Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of California San Diego

LigandPNGBDBM50241504(3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxylic aci...)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition assay using matrix metalloproteinases.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
University Of California San Diego

LigandPNGBDBM50241504(3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxylic aci...)
Affinity DataIC50:  240nMAssay Description:Inhibition assay using matrix metalloproteinases.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of California San Diego

LigandPNGBDBM50241504(3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxylic aci...)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of human MMP2 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
University Of California San Diego

LigandPNGBDBM50241504(3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxylic aci...)
Affinity DataIC50:  240nMAssay Description:Inhibition of human MMP3 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50241504(3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxylic aci...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human MMP1 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed