BDBM50241570 (24E)-3beta-hydroxy-7,24-euphadien-26-oic acid::CHEMBL519411

SMILES C[C@@H](CC\C=C(/C)C(O)=O)[C@]1(C)CC[C@]2(C)C3=CC[C@H]4C(C)(C)[C@@H](O)CC[C@]4(C)[C@H]3CC[C@@]12C

InChI Key InChIKey=PSSOTMPEBLYOAS-MGULVPRESA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50241570   

TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50241570((24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | C...)
Affinity DataKi:  2.80E+3nMAssay Description:Inhibition of rat recombinant DNA polymerase beta after 20 mins by uncompetitive inhibition assay in presence of activated calf thymus DNA and 0.1 mg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50241570((24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | C...)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of rat recombinant DNA polymerase beta after 20 mins by noncompetitive inhibition assay in presence of activated calf thymus DNA and 0.1 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50241570((24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | C...)
Affinity DataKi:  2.80E+4nMAssay Description:Inhibition of rat recombinant DNA polymerase beta after 20 mins by uncompetitive inhibition assay in presence of [3H]dTTP and 0.1 mg/mL BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50241570((24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | C...)
Affinity DataKi:  8.20E+4nMAssay Description:Inhibition of rat recombinant DNA polymerase beta after 20 mins by noncompetitive inhibition assay in presence of [3H]dTTP and 0.1 mg/mL BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50241570((24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | C...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of rat recombinant DNA polymerase beta after 60 mins in presence of 0.1 mg/mL BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50241570((24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | C...)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of rat recombinant DNA polymerase beta after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed