BDBM50241990 CHEMBL502489::Camboginol::Garcinol::Garcinol, 1
SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6@@H](-[#6][C@@]12[#6]-[#6@@H](-[#6]\[#6]=[#6](\[#6])-[#6])C([#6])([#6])[C@@]([#6]\[#6]=[#6](\[#6])-[#6])([#6](=O)-[#6](-[#6](=O)-c3ccc(-[#8])c(-[#8])c3)-[#6]1=O)[#6]2=O)-[#6](-[#6])=[#6]
InChI Key InChIKey=YESGFVCPMZHDNK-FIXRDIOOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50241990
TargetHistone acetyltransferase p300(Human)
Jawaharlal Nehru Centre For Advanced Scientific Research
Curated by ChEMBL
Jawaharlal Nehru Centre For Advanced Scientific Research
Curated by ChEMBL
Affinity DataKi: 4.90E+3nMAssay Description:Inhibition of HAT p300 catalytic domain by equilibrium dialysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using [3H]-acetyl-CoA assessed as acetate incorp...More data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Human)
Jawaharlal Nehru Centre For Advanced Scientific Research
Curated by ChEMBL
Jawaharlal Nehru Centre For Advanced Scientific Research
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant histone acetyltransferase p300 (unknown origin) using dH3-H4 tetramer and [3H]-acetyl-CoA assessed as acetate incorporation...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of yeast histone acetyltransferase Gcn5-Ada2-Ada3 complex using tetramer and [3H]-acetyl-CoA assessed as acetate incorporation after 30 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of HAT PCAFMore data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Human)
Jawaharlal Nehru Centre For Advanced Scientific Research
Curated by ChEMBL
Jawaharlal Nehru Centre For Advanced Scientific Research
Curated by ChEMBL
Affinity DataKd: 1.80E+3nMAssay Description:Binding affinity to HAT p300 catalytic domain by fluorometric titrationMore data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Human)
Jawaharlal Nehru Centre For Advanced Scientific Research
Curated by ChEMBL
Jawaharlal Nehru Centre For Advanced Scientific Research
Curated by ChEMBL
Affinity DataKd: 6.60E+3nMAssay Description:Binding affinity to HAT p300 catalytic domain by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Human)
Jawaharlal Nehru Centre For Advanced Scientific Research
Curated by ChEMBL
Jawaharlal Nehru Centre For Advanced Scientific Research
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of HAT p300More data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Human)
Jawaharlal Nehru Centre For Advanced Scientific Research
Curated by ChEMBL
Jawaharlal Nehru Centre For Advanced Scientific Research
Curated by ChEMBL
Affinity DataKd: 400nMT: 37°CAssay Description:The p300 activity assays were performed by a colorimetric kit (JM-K322-100, MBL) using active recombinant p300/HAT as positive control and acetyl-CoA...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 1-alpha/beta(Human)
University of Salerno
Curated by ChEMBL
University of Salerno
Curated by ChEMBL
Affinity DataKd: 1.69E+4nMAssay Description:Binding affinity to STAT1 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair