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BDBM50242019 CHEMBL4072776

SMILES: CC(c1ccc2ncc(cc2c1)-c1ccc(F)cc1)n1nnc2ncc(nc12)-c1ccncc1

InChI Key: InChIKey=HKFKSBJVXOOASU-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50242019   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50242019
PNG
(CHEMBL4072776)
Show SMILES CC(c1ccc2ncc(cc2c1)-c1ccc(F)cc1)n1nnc2ncc(nc12)-c1ccncc1
Show InChI InChI=1/C26H18FN7/c1-16(34-26-25(32-33-34)30-15-24(31-26)18-8-10-28-11-9-18)19-4-7-23-20(12-19)13-21(14-29-23)17-2-5-22(27)6-3-17/h2-16H,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.60n/an/an/an/an/an/a



Shanghai Pharmaceuticals Holding Co., Ltd.

Curated by ChEMBL


Assay Description
Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assay


Eur J Med Chem 134: 147-158 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.085
BindingDB Entry DOI: 10.7270/Q2CF9S81
More data for this
Ligand-Target Pair