BDBM50242196 CHEMBL4069423

SMILES OC(=O)CCc1nc2cc(Cl)ccc2s1

InChI Key InChIKey=UMBLVHSXXWQLDL-UHFFFAOYSA-N

Data  2 IC50  2 Kd

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50242196   

TargetHistone deacetylase 6(Homo sapiens (Human))
Entremed

Curated by ChEMBL
LigandPNGBDBM50242196(CHEMBL4069423)
Affinity DataKd:  4.00E+4nMAssay Description:Inhibition of HIV-1 protease in 5%DMSOMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Entremed

Curated by ChEMBL
LigandPNGBDBM50242196(CHEMBL4069423)
Affinity DataIC50:  5.50E+4nMAssay Description:Displacement of N-terminal FITC-labeled RLRGG from N-terminal AviTag/C-terminal His6-tagged HDAC6 ZnF-UBD (unknown origin) expressed in Escherichia c...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Entremed

Curated by ChEMBL
LigandPNGBDBM50242196(CHEMBL4069423)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of HIV-1 protease in 5%DMSOMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Entremed

Curated by ChEMBL
LigandPNGBDBM50242196(CHEMBL4069423)
Affinity DataKd:  6.00E+4nMAssay Description:Binding affinity to N-terminal Avi-tagged/C-terminal His6-tagged HDAC6 zinc-finger ubiquitin binding domain (1109 to 1215 residues)(unknown origin) e...More data for this Ligand-Target Pair