BDBM50242637 CHEMBL504374::N,N-dimethyl-5-phenethyl-2H-tetrazole-2-carboxamide

SMILES CN(C)C(=O)n1nnc(CCc2ccccc2)n1

InChI Key InChIKey=LTQAGBUYSHHPOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242637   

TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50242637(CHEMBL504374 | N,N-dimethyl-5-phenethyl-2H-tetrazo...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of FAAH mediated [14C]anadamide hydrolysis in rat brain after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-alpha(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50242637(CHEMBL504374 | N,N-dimethyl-5-phenethyl-2H-tetrazo...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed