BDBM50243259 (R)-1-(5-phenyl-3-(piperidin-3-ylcarbamoyl)thiophen-2-yl)urea::CHEMBL519226

SMILES NC(=O)Nc1sc(cc1C(=O)N[C@@H]1CCCNC1)-c1ccccc1

InChI Key InChIKey=UXZRCIBKIDILEF-GFCCVEGCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50243259   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243259((R)-1-(5-phenyl-3-(piperidin-3-ylcarbamoyl)thiophe...)
Affinity DataIC50:  170nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed