BDBM50243260 (R)-1-(3-((1-methylpiperidin-3-yl)carbamoyl)-5-phenylthiophen-2-yl)urea::CHEMBL486233

SMILES CN1CCC[C@H](C1)NC(=O)c1cc(sc1NC(N)=O)-c1ccccc1

InChI Key InChIKey=UBZNCKMMWOCMGD-CYBMUJFWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50243260   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243260((R)-1-(3-((1-methylpiperidin-3-yl)carbamoyl)-5-phe...)
Affinity DataIC50:  160nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed