BDBM50243420 1-(3-carbamoyl-5-(4-(trifluoromethoxy)phenyl)thiophen-2-yl)urea::CHEMBL509599

SMILES NC(=O)Nc1sc(cc1C(N)=O)-c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=RIYQWXBEGJBVDI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50243420   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243420(1-(3-carbamoyl-5-(4-(trifluoromethoxy)phenyl)thiop...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed