BDBM50243453 (2S,3R)-2-amino-3-hydroxy-1-(pyrrolidin-1-yl)butan-1-one::CHEMBL459438

SMILES C[C@@H](O)[C@H](N)C(=O)N1CCCC1

InChI Key InChIKey=PVIKRKVTPIEUAJ-RQJHMYQMSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50243453   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50243453((2S,3R)-2-amino-3-hydroxy-1-(pyrrolidin-1-yl)butan...)
Affinity DataKi:  4.90E+3nMAssay Description:In vitro test for inhibitory activity against human dipeptidyl peptidase IV.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243453((2S,3R)-2-amino-3-hydroxy-1-(pyrrolidin-1-yl)butan...)
Affinity DataIC50:  2.30E+5nMAssay Description:Inhibition of DPP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243453((2S,3R)-2-amino-3-hydroxy-1-(pyrrolidin-1-yl)butan...)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of DPP8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50243453((2S,3R)-2-amino-3-hydroxy-1-(pyrrolidin-1-yl)butan...)
Affinity DataIC50:  9.80E+4nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243453((2S,3R)-2-amino-3-hydroxy-1-(pyrrolidin-1-yl)butan...)
Affinity DataIC50:  3.42E+4nMAssay Description:Inhibition of DPP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed