BDBM50243646 CHEMBL471544::benzyl (S)-5-amino-6-((S)-2-cyanopyrrolidin-1-yl)-6-oxohexylcarbamate

SMILES N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C#N

InChI Key InChIKey=WAVJGCCRPYAHLF-IRXDYDNUSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50243646   

TargetDipeptidyl peptidase 9(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243646(CHEMBL471544 | benzyl (S)-5-amino-6-((S)-2-cyanopy...)
Affinity DataIC50:  212nMAssay Description:Inhibition of DPP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243646(CHEMBL471544 | benzyl (S)-5-amino-6-((S)-2-cyanopy...)
Affinity DataIC50:  840nMAssay Description:Inhibition of DPP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase IV(Porphyromonas gingivalis)
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50243646(CHEMBL471544 | benzyl (S)-5-amino-6-((S)-2-cyanopy...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Porphyromonas gingivalis N-terminal His-tagged DPP4 expressed in Escherichia coli using Gly-Pro-p-nitroanilide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243646(CHEMBL471544 | benzyl (S)-5-amino-6-((S)-2-cyanopy...)
Affinity DataIC50:  240nMAssay Description:Inhibition of DPP8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243646(CHEMBL471544 | benzyl (S)-5-amino-6-((S)-2-cyanopy...)
Affinity DataIC50:  35nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed