BDBM50243665 (R)-1-(5-phenyl-3-(quinuclidin-8-ylcarbamoyl)thiophen-2-yl)urea::CHEMBL512706

SMILES NC(=O)Nc1sc(cc1C(=O)N[C@H]1CN2CCC1CC2)-c1ccccc1

InChI Key InChIKey=MUMLSZXBXFEQAV-HNNXBMFYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50243665   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243665((R)-1-(5-phenyl-3-(quinuclidin-8-ylcarbamoyl)thiop...)
Affinity DataIC50:  980nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed