BDBM50243671 (S)-N-(trans-4-Fluorocyclohexyl)-4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)-N-cyclopropylbenzamide::CHEMBL471930

SMILES C[C@](O)(c1ccc(cc1)C(=O)N(C1CC1)[C@H]1CC[C@H](F)CC1)C(F)(F)F

InChI Key InChIKey=MCQZOJFPSRKRQW-MPGHIAIKSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50243671   

LigandPNGBDBM50243671((S)-N-(trans-4-Fluorocyclohexyl)-4-(1,1,1-trifluor...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 11beta-HSD2 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50243671((S)-N-(trans-4-Fluorocyclohexyl)-4-(1,1,1-trifluor...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of 11beta-HSD1 in human adipocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50243671((S)-N-(trans-4-Fluorocyclohexyl)-4-(1,1,1-trifluor...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells in presence of 3% human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50243671((S)-N-(trans-4-Fluorocyclohexyl)-4-(1,1,1-trifluor...)
Affinity DataIC50:  36nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50243671((S)-N-(trans-4-Fluorocyclohexyl)-4-(1,1,1-trifluor...)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of human cloned 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed