BDBM50243970 (+/-)N-(1-Biphenyl-4-yl-2-morpholin-4-yl-ethyl)-2-(6,7-dichloro-3-oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl)-N-methyl-acetamide::CHEMBL453074

SMILES CN(C(CN1CCOCC1)c1ccc(cc1)-c1ccccc1)C(=O)CN1C(=O)COc2cc(Cl)c(Cl)cc12

InChI Key InChIKey=ODYPAHVIPOBHBB-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50243970   

TargetUrotensin-2 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243970((+/-)N-(1-Biphenyl-4-yl-2-morpholin-4-yl-ethyl)-2-...)
Affinity DataKi:  13nMAssay Description:Binding affinity to human urotensin2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243970((+/-)N-(1-Biphenyl-4-yl-2-morpholin-4-yl-ethyl)-2-...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243970((+/-)N-(1-Biphenyl-4-yl-2-morpholin-4-yl-ethyl)-2-...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243970((+/-)N-(1-Biphenyl-4-yl-2-morpholin-4-yl-ethyl)-2-...)
Affinity DataEC50:  320nMAssay Description:Agonist activity at kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed