BDBM50244118 CHEMBL518197::ethyl 12-oxo-15-[2-(trimethylsilyl)ethynyl]-2,4,11-triazatetracyclo[11.4.0.0^{2,6}.0^{7,11}]heptadeca-1(17),3,5,13,15-pentaene-5-carboxylate

SMILES CCOC(=O)c1ncn-2c1C1CCCN1C(=O)c1cc(ccc-21)C#C[Si](C)(C)C

InChI Key InChIKey=UDLTUJYBFNCMJX-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50244118   

TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Moltech

Curated by ChEMBL
LigandPNGBDBM50244118(CHEMBL518197 | ethyl 12-oxo-15-[2-(trimethylsilyl)...)
Affinity DataKd:  4nMAssay Description:Binding affinity to GABAA alpha-5-beta-2-gamma-2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Moltech

Curated by ChEMBL
LigandPNGBDBM50244118(CHEMBL518197 | ethyl 12-oxo-15-[2-(trimethylsilyl)...)
Affinity DataKd:  200nMAssay Description:Binding affinity to GABAA alpha-1-beta-2-gamma-2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed