BDBM454169 BDBM50246180::US10716791, Code KP-302

SMILES Cn1cccc1C(=O)N[C@@H](CCn1ccnc1)C(=O)NCc1ccccc1

InChI Key InChIKey=XLISVTDEJLYVTB-KRWDZBQOSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 454169   

TargetProtein-arginine deiminase type-2(Mus musculus)
University Health Network

US Patent
LigandPNGBDBM454169(BDBM50246180 | US10716791, Code KP-302)
Affinity DataKi:  6.00E+4nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-2(Mus musculus)
University Health Network

US Patent
LigandPNGBDBM454169(BDBM50246180 | US10716791, Code KP-302)
Affinity DataKi:  6.00E+4nMAssay Description:Inhibition of full length mouse GST-tagged PAD2 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein-arginine deiminase type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM454169(BDBM50246180 | US10716791, Code KP-302)
Affinity DataKi:  1.55E+5nMAssay Description:Inhibition of full length human GST-tagged PAD1 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM454169(BDBM50246180 | US10716791, Code KP-302)
Affinity DataKi:  1.80E+5nMAssay Description:Inhibition of full length human GST-tagged PAD4 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM454169(BDBM50246180 | US10716791, Code KP-302)
Affinity DataKi:  1.80E+5nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-1(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM454169(BDBM50246180 | US10716791, Code KP-302)
Affinity DataKi:  4.02E+5nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent