BDBM50246197 CHEMBL520074::N-(4-(3-chloro-4-methoxybenzylamino)-8-allyl-7-methoxyquinazolin-6-yl)propionamide

SMILES CCC(=O)Nc1cc2c(NCc3ccc(OC)c(Cl)c3)ncnc2c(CC=C)c1OC

InChI Key InChIKey=RZNXAUVMTXWAMP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246197   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Chong Kun Dang Research Institute

Curated by ChEMBL
LigandPNGBDBM50246197(CHEMBL520074 | N-(4-(3-chloro-4-methoxybenzylamino...)
Affinity DataIC50:  18nMAssay Description:Inhibition of bovine PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Chong Kun Dang Research Institute

Curated by ChEMBL
LigandPNGBDBM50246197(CHEMBL520074 | N-(4-(3-chloro-4-methoxybenzylamino...)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of human recombinant PDE11More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed