BDBM50247150 5'-phenylthio-ImmH::CHEMBL474328::US9290501, (B)

SMILES O[C@@H]1[C@@H](CSc2ccccc2)N[C@H]([C@@H]1O)c1c[nH]c2c1nc[nH]c2=O

InChI Key InChIKey=RILVLBFFRDXSEY-JMGFVUJMSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50247150   

TargetS-methyl-5'-thioinosine phosphorylase(Pseudomonas aeruginosa)
Albert Einstein College Of Medicine

US Patent
LigandPNGBDBM50247150(5'-phenylthio-ImmH | CHEMBL474328 | US9290501, (B))
Affinity DataKi:  0.0350nM ΔG°:  -14.3kcal/molepH: 7.4 T: 2°CAssay Description:Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College Of Medicine Of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50247150(5'-phenylthio-ImmH | CHEMBL474328 | US9290501, (B))
Affinity DataKi:  160nMAssay Description:Initial binding affinity to wild type human PNPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed