BDBM50247599 (Z)-5-(4'-Hydroxybenzylidene)-2-thioxothiazolidin-4-one::5-(4-hydroxybenzylidene)-2-thioxothiazolidin-4-one::CHEMBL487697

SMILES Oc1ccc(C=C2SC(S)=NC2=O)cc1

InChI Key InChIKey=RAYIDZVPIAJJPF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50247599   

TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50247599((Z)-5-(4'-Hydroxybenzylidene)-2-thioxothiazolidin-...)
Affinity DataIC50:  1.69E+4nMAssay Description:Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50247599((Z)-5-(4'-Hydroxybenzylidene)-2-thioxothiazolidin-...)
Affinity DataIC50:  1.01E+7nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50247599((Z)-5-(4'-Hydroxybenzylidene)-2-thioxothiazolidin-...)
Affinity DataIC50:  4.55E+3nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed