BDBM50247803 Beta-Funeltrexamine::CHEMBL473136::beta-funaltrexamine::methyl (2E)-3-{[(1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-14-yl]carbamoyl}prop-2-enoate::methyl 3-[4-cyclopropylmethyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-ylcarbamoyl]-(E)-2-propenoate
SMILES COC(=O)\C=C\C(=O)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45
InChI Key InChIKey=PQKHESYTSKMWFP-WZJCLRDWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50247803
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Compound was evaluated for binding affinity against [3H]- DAMGO labeled mu opioid receptor in guinea-pig brain homogenate.More data for this Ligand-Target Pair
Affinity DataKi: 0.410nMAssay Description:Activity at monocloned mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.410nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Compound was evaluated for binding affinity against [3H]- U-69593 labeled kappa1 opioid receptor in guinea-pig brain homogenate.More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]U69593 from KOR in guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.940nMAssay Description:Displacement of [3H]norBNI from monocloned kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.940nMAssay Description:Displacement of [3H]norBNI from kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Compound was evaluated for binding affinity against [3H]- Cl-DPDPE labeled Opioid receptor delta 1 in guinea-pig brain homogenate.More data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of [3H]NTI from delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of [3H]NTI from monocloned delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 67nMAssay Description:Compound was evaluated for kappa opioid receptor mediated agonistic effect in electrically stimulated guinea-pig ileumMore data for this Ligand-Target Pair
TargetNeuropeptides B/W receptor type 1(Human)
Addiction Research Foundation
Curated by PDSP Ki Database
Addiction Research Foundation
Curated by PDSP Ki Database
Affinity DataIC50: 4.80nMAssay Description:Inhibitory concentration against mu-opioid receptor in guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Displacement of beta-[3H]FNA from mu opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Inhibitory concentration against mu-opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rat)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:The compound was tested for binding affinity against opioid receptor in rat brain membranes, using [3H]dihydromorphine as the radioligandMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Mouse)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 82nMAssay Description:Compound was tested for agonist activity against opioid receptor in mouse vas deferens preparationMore data for this Ligand-Target Pair