BDBM50247946 2-(1-(4-methyl-3-(trifluoromethyl)phenyl)-1H-1,2,3-triazol-4-yl)-N-(pyridin-4-ylmethyl)aniline::CHEMBL523320

SMILES Cc1ccc(cc1C(F)(F)F)-n1cc(nn1)-c1ccccc1NCc1ccncc1

InChI Key InChIKey=RPXAVKZRWOMBEP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50247946   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Decode

Curated by ChEMBL
LigandPNGBDBM50247946(2-(1-(4-methyl-3-(trifluoromethyl)phenyl)-1H-1,2,3...)
Affinity DataIC50:  140nMAssay Description:Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Decode

Curated by ChEMBL
LigandPNGBDBM50247946(2-(1-(4-methyl-3-(trifluoromethyl)phenyl)-1H-1,2,3...)
Affinity DataIC50:  180nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Decode

Curated by ChEMBL
LigandPNGBDBM50247946(2-(1-(4-methyl-3-(trifluoromethyl)phenyl)-1H-1,2,3...)
Affinity DataIC50:  110nMAssay Description:Inhibition of VEGFR1 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed