BDBM50248311 (R)-1-(4-tert-butylphenylsulfonyl)-2-methyl-4-(pyridin-4-ylmethyl)piperazine::CHEMBL473955

SMILES C[C@@H]1CN(Cc2ccncc2)CCN1S(=O)(=O)c1ccc(cc1)C(C)(C)C

InChI Key InChIKey=WLDFBXGCKXAERK-QGZVFWFLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248311   

LigandPNGBDBM50248311((R)-1-(4-tert-butylphenylsulfonyl)-2-methyl-4-(pyr...)
Affinity DataIC50:  11.3nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50248311((R)-1-(4-tert-butylphenylsulfonyl)-2-methyl-4-(pyr...)
Affinity DataIC50:  146nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed