BDBM50248523 CHEMBL489330::N-hydroxy-3-(2-phenethyl-1-(3-(pyrrolidin-1-yl)propyl)-1H-benzo[d]imidazol-5-yl)acrylamide::US10201527, Compound 82::US10736881, Compound 82::US8551988, 82

SMILES ONC(=O)\C=C\c1ccc2n(CCCN3CCCC3)c(CCc3ccccc3)nc2c1

InChI Key InChIKey=LVLUMZOFEFJVAS-SDNWHVSQSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50248523   

TargetHistone deacetylase 1(Homo sapiens (Human))
Mei Pharma

US Patent
LigandPNGBDBM50248523(CHEMBL489330 | N-hydroxy-3-(2-phenethyl-1-(3-(pyrr...)
Affinity DataIC50:  304nMAssay Description:The assay have been carried out in a 96 well format and the BIOMOL using a fluorescent-based HDAC activity assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Mei Pharma

US Patent
LigandPNGBDBM50248523(CHEMBL489330 | N-hydroxy-3-(2-phenethyl-1-(3-(pyrr...)
Affinity DataIC50:  304nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Mei Pharma

US Patent
LigandPNGBDBM50248523(CHEMBL489330 | N-hydroxy-3-(2-phenethyl-1-(3-(pyrr...)
Affinity DataIC50:  304nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Mei Pharma

US Patent
LigandPNGBDBM50248523(CHEMBL489330 | N-hydroxy-3-(2-phenethyl-1-(3-(pyrr...)
Affinity DataIC50:  310nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed