BDBM50248855 14beta-Acetoyloxy-17-cyclopropylmethyl-4,5alpha-epoxy-3-hydroxy-6beta-(cinnamoylamino)morphinan::CHEMBL472583

SMILES CC(=O)O[C@]12CC[C@@H](NC(=O)\C=C\c3ccccc3)[C@@H]3Oc4c5c(C[C@H]1N(CC1CC1)CC[C@@]235)ccc4O

InChI Key InChIKey=OSVAKAHPJDCGIG-KAPPCOJISA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50248855   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50248855(14beta-Acetoyloxy-17-cyclopropylmethyl-4,5alpha-ep...)
Affinity DataKi:  0.210nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membrane by liquid scintillation and luminescence counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50248855(14beta-Acetoyloxy-17-cyclopropylmethyl-4,5alpha-ep...)
Affinity DataKi:  0.590nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membrane by liquid scintillation and luminescence counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50248855(14beta-Acetoyloxy-17-cyclopropylmethyl-4,5alpha-ep...)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membrane assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50248855(14beta-Acetoyloxy-17-cyclopropylmethyl-4,5alpha-ep...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at rat mu opioid receptor expressed in rat C6 cell membrane assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed