BDBM50249221 5-((2R)-2-aminocyclohexylamino)-7-(3,5-dimethoxyphenylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide::CHEMBL471948

SMILES COc1cc(Nc2nc(NC3CCCC[C@H]3N)n3ncnc3c2C(N)=O)cc(OC)c1

InChI Key InChIKey=RVIMFNLCTIXVKN-GICMACPYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50249221   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL

LigandBDBM50249221(5-((2R)-2-aminocyclohexylamino)-7-(3,5-dimethoxyph...)Copy SMILESCopy InChI

Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant Syk (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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