BDBM50249489 CHEMBL514344::N-(3-(1H-Benzo[d]imidazol-2-yl)-4-chlorophenyl)-3,4,5-triethoxybenzamide

SMILES CCOc1cc(cc(OCC)c1OCC)C(=O)Nc1ccc(Cl)c(c1)-c1nc2ccccc2[nH]1

InChI Key InChIKey=VQOJFGFKIVFMDH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249489   

TargetSonic hedgehog protein(Mouse)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50249489(CHEMBL514344 | N-(3-(1H-Benzo[d]imidazol-2-yl)-4-c...)
Affinity DataIC50:  30nMAssay Description:Inhibition of SHH-mediated mouse C3H10T1/2 cells differentiation into osteoblasts by alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSonic hedgehog protein(Mouse)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50249489(CHEMBL514344 | N-(3-(1H-Benzo[d]imidazol-2-yl)-4-c...)
Affinity DataIC50:  97.9nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed