BDBM50249527 CHEMBL470533::ethyl 5-(2,5-dimethylphenylsulfonamido)-2-propylbenzofuran-3-carboxylate

SMILES CCCc1oc2ccc(NS(=O)(=O)c3cc(C)ccc3C)cc2c1C(=O)OCC

InChI Key InChIKey=JYXFTAMWZQRAMQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249527   

Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50249527(CHEMBL470533 | ethyl 5-(2,5-dimethylphenylsulfonam...)
Affinity DataIC50:  5.87E+3nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximity assay in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50249527(CHEMBL470533 | ethyl 5-(2,5-dimethylphenylsulfonam...)
Affinity DataIC50:  980nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximity assay in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed